Author: Gianpiero Pescarmona
Extracellular cAMP may act as a signal in multiple environments.
The best studied model is Dictyostelium discoideum
Computational modelling suggests dynamic interactions between Ca2+, IP3 and G protein-coupled modules are key to robust Dictyostelium aggregation. 2009
Three modules interconnected support our model for cAMP oscillations in Dictyostelium.
Close interdependence between the Ca2+, IP3 and G protein-coupled modules
Dynamic localization of G proteins in Dictyostelium discoideum, 2009