Author: Di Gioia Matteo
Date: 20/07/2007



The hyperidrosis, or excessive perspiration, prevalently locate itself in the zones in which the number of the glands sudoripare is higher.

It Shows with bigger intensity during the wake, with maximum instalments in concomitance of special actions or emotional states.

  1. primary hyperidrosis:unknown cause.
  2. secondary hyperidrosis: due to some conditions that can promote excessive sweating.


  • Sex: It regards in the same measure males and females, interesting about the 3% of the population
  • Age: Primary Hyperhidrosis usually starts during childhood or adolescence and persists all life.
  • Seasonality: perspiration increases in summer because of high temperature and can attenuates in winter with low temperature.


  • Facial Hyperhidrosis: Sweat pouring down from the forehead in conditions of stress can be very distressful, inducing the patient to think that others may consider him/her nervous and insecure.
  • Palmar Hyperhidrosis: Excessive sweating of the hands is, generally, by far the most distressing condition. The hands are much more exposed in social and professional activities than any other part of our body. Many individuals with this condition are limited in their choice of profession, because unable to manipulate materials sensitive to humidity (paper etc) or reluctant to shake hands; some patients arrive to the point to avoid social contact. The degree of sweating varies and may range from moderate moisture to dripping. Most patients notice that their hands not only feel moist, but also cold.
  • Axillary Hyperhidrosis: Also hyperhidrosis of the armpits can be embarrassing causing large wet marks and sometimes a white halo of salt from sweating on the cloths.It involves extreme, dripping sweat in the armpits, with constant odor that is usually resistant to all deodorants. Axillary sweating may be present, alone, or in conjunction with any or all other types of hyperhidrosis.
  • Plantar Hyperhidrosis:who is affeccted, complains of bad foot odor. The most common problems with Plantar Hyperhidrosis are athlete’s feet, blisters, infection and rotting of socks.
  • Other locations: Less frequently, it is located only to the trunk and/or the thighs.
  • Many individuals suffer form a combination of the above cathegories.
  • Sweating can appear suddenly or manifest itself more continuously.
  • It can be elicited by high outside temperatures or emotional stress, or appears without any obvious reason.
  • Generally, it worsens during the warm season and gets better during winter.


  • based upon the patient’s history of wet armpits and massive sweating of the palms and soles after emotional stress.
  • Minor’s Iodine starch test: After application of iodine liquid followed by starch powder, the hyperhidrotic area becomes visible as a distinctive violet patch, enabling the clinician to precisely define the region of treatment as well as the intensity of hyperhidrosis
  • Ninhydrine Test
  • Self Evaluation Scale: useless

Causes of Secondary Hyperhidrosis:

Causes of Primary Hyperhidrosis:

Patient Risk Factors:

Tissue Specific Risk Factors

  • Vascular: there is no evidence of correlation with Hyperhidrosis
  • physiopathological:(due to tissue function and activity)


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