STKs - Serine/Threonine Kinases phosphorylate the OH group of protein serine or threonine.
At least 20% of the human protein kinases are serine/threonine kinases (STK) ???
Activity of these protein kinases can be regulated by specific events
- DNA damage
- numerous chemical signals
- cAMP/cGMP
- Diacylglycerol
- Ca2+/calmodulin
