Plasma Contact System
Serum Proteins

the network of many pathways: hemocoagulation:, fibrinolylis , kininogenesis, complement and angiotensinogenesis

The contact system consists of the two proenzyme factor XII (FXII) and plasma prekallikrein (PK), as well as the non-enzymatic procofactor high-molecular-weight-kininogen (HMWK): that locally assemble and become activated on negatively charged surfaces

by Enrico Badellino