Chemokines receptors
Chemokines

Author: Gianpiero Pescarmona
Date: 23/11/2014

Description

C-C chemokine receptor type 3
Gene
CCR3

Functioni
Receptor for a C-C type chemokine. Binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES and MIP-1 delta. Subsequently transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection.

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