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The biosynthesis of E-series resolvins from EPA and D-series resolvins, PD1, and maresins from DHA.
Caymanchem: measurement of lipid mediators of resolution of inflammation
The D-series resolvins (RvD1, RvD2, RvD3, RvD4, RvD5, and RvD6) are synthesized from DHA by acetylated COX-2 or 15-LO. D-Series resolvin synthesis results via formation of 17-hydroperoxydocosahexaenoic acid (17-HpDHA) and 17-hydroxydocosahexaenoic acid (17-HDHA).
