Pharmacogenomics is the branch of pharmacology which deals with the influence of genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with a drug's efficacy or toxicity. By doing so, pharmacogenomics aims to develop rational means to optimise drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Such approaches promise the advent of personalized medicine; in which drugs and drug combinations are optimized for each individual's unique genetic and environmental makeup.
Mdp: Mutations and Drugs Porta
Creato da ricercatori dell'Università di Trieste, Unimore e del Laboratorio Nazionale Cib di Area Science Park, Mdp è a oggi il più grande database per l'identificazione sistematica di indicatori genetici della sensibilità dei tumori ai farmaci e per la scoperta di molecole capaci di agire specificamente sulle cellule tumorali.
