DEFINITION
Ferroportin is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters)
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CHEMICAL STRUCTURE AND IMAGES
When relevant for the function
- Primary structure
- Secondary structure
- Tertiary structure
- Quaternary structure
Protein Aminoacids Percentage
The Protein Aminoacids Percentage gives useful information on the local environment and the metabolic status of the cell (starvation, lack of essential AA, hypoxia)
SYNTHESIS AND TURNOVER
mRNA synthesis
protein synthesis
post-translational modifications
degradation
CELLULAR FUNCTIONS
cellular localization,
biological function
- Enzymes
- Cell signaling and Ligand transport
- Structural proteins
REGULATION
MTP1 expression in RES cells of the spleen, liver, and bone marrow is down-regulated by inflammation.
Regulation of Reticuloendothelial Iron Transporter MTP1 (Slc11a3) by Inflammation 2002
DIAGNOSTIC USE
