Author: Gianpiero Pescarmona Date: 02/04/2010
Synapse is a structure that permits a neuron to pass an electrical or chemical signal to another cell.
. B-50/GAP-43 and RC3/neurogranin are two defined neuronal PKC substrates with different synaptic localization. [1997]
Synaptic proteins and receptors defects in autism spectrum disorders, 2014
In the NMJ: 1)Presynaptic proteins: VGCC - VGCC-Ab VGKC - VGKC-Ab Snap25 - BoNT/A,C,E Syntaxin - BoNT/C Synaptobrevin - BoNT/B,D,F,G, TeNT Neurexin - Alpha-Latrotoxin Latrophilin - Alpha-Latrotoxin Protein Tyrosine Phosphatase sigma (PTPĪ) - Alpha-Latrotoxin
2)Cholinesterase - Cholinesterase inhibitors (Physostigmine, Organophosphate Insecticides)
3)Postsynaptic proteins: AchRm - AchR-Ab, alfa-Bungarotoxin, D-tubocurarine MuSK - MuSK-Ab Lrp4 - Lrp4-Ab
In the muscle: Titin - Titin-Ab RyR - RyR-Ab