Synapse
Neuron

Author: Gianpiero Pescarmona
Date: 02/04/2010

Description

Synapse is a structure that permits a neuron to pass an electrical or chemical signal to another cell.

Synaptic cleft proteins

Neurexin and Neuroligin

. B-50/GAP-43 and RC3/neurogranin are two defined neuronal PKC substrates with different synaptic localization. [1997]

Synaptic proteins and receptors defects in autism spectrum disorders, 2014

Comments
2013-08-25T14:06:56 - Giusi Morando

In the NMJ:
1)Presynaptic proteins:
VGCC - VGCC-Ab
VGKC - VGKC-Ab
Snap25 - BoNT/A,C,E
Syntaxin - BoNT/C
Synaptobrevin - BoNT/B,D,F,G, TeNT
Neurexin - Alpha-Latrotoxin
Latrophilin - Alpha-Latrotoxin
Protein Tyrosine Phosphatase sigma (PTPĪƒ) - Alpha-Latrotoxin

2)Cholinesterase - Cholinesterase inhibitors (Physostigmine, Organophosphate Insecticides)

3)Postsynaptic proteins:
AchRm - AchR-Ab, alfa-Bungarotoxin, D-tubocurarine
MuSK - MuSK-Ab
Lrp4 - Lrp4-Ab

In the muscle:
Titin - Titin-Ab
RyR - RyR-Ab

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