A short yet comprehensive description
ANALYTICAL TRICKS AND TIPS
THE BIOLOGICAL CONTEXT
THE NORMAL RANGE
Specificity, sensitivity etc.
3 calculated ratios
- Carnitine Hypothyroidism
- Urinary excretion of carnitine in patients with hyperthyroidism and hypothyroidism: augmentation by thyroid hormone. 1977
In contrast, carnitine excretion was markedly reduced in hypothyroid patients.
- Muscle carnitine in hypo- and hyperthyroidism. 2005 Weakness is common in both hyper- and hypothyroidism, and skeletal muscle L-carnitine may play a role in this regard, as suggested by studies indicating abnormal levels of carnitine in serum and urine of patients with thyroid dysfunction. Skeletal muscle samples were obtained for carnitine analysis from control subjects, and from hyperthyroid and hypothyroid patients before and after treatment. There was a significant reduction in carnitine, especially the esterified portion, in hyperthyroid individuals, with a return to normal as euthyroid status was regained. In hypothyroid patients, there was a trend for carnitine to be lower than normal and for improvement once euthyroid status was attained. Our data indicate that muscle carnitine levels are affected by both hypo- and hyperthyroidism. A decrease in muscle carnitine in both conditions may contribute to thyroid myopathy.
Acetyl-L-carnitine and Neuroprotection
PROs and CONTROs