SGLT (Sodium Glucose Cotransporters)
Glucose Transport

Author: Gianpiero Pescarmona
Date: 20/05/2016

Description

DEFINITION

A short protein description with the molecular wheight, isoforms, etc...

The SGLT family comprises Na+-dependent:

  • glucose co-transporters (SGLT1 and SGLT2),
  • the glucose sensor SGLT3,
  • the widely distributed inositol and multivitamin transporters SGLT4 and SGLT6,9
  • the thyroid iodide transporter SGLT5.

External links not available on Wikipedia have to be added here

THE GENE

DatabaseLink
WikigenesACADM
GeneCards"URL":
Your Favorite Gene Sigma"URL":

Wikigenes includes links to

  • NCBI Gene
  • NCBI SNP
  • iHOP resource
  • OMIM
  • SNPedia
  • UniProt
  • Ensembl
  • HGNC

CHEMICAL STRUCTURE AND IMAGES

When relevant for the function

  • Primary structure
  • Secondary structure
  • Tertiary structure
  • Quaternary structure


Protein Aminoacids Percentage
The Protein Aminoacids Percentage gives useful information on the local environment and the metabolic status of the cell (starvation, lack of essential AA, hypoxia)

Protein Aminoacids Percentage (xls file)

SYNTHESIS AND TURNOVER

mRNA synthesis
protein synthesis

post-translational modifications
degradation

CELLULAR FUNCTIONS

cellular localization,
biological function

  • Enzymes
DatabaseLink
BRENDA - The Comprehensive Enzyme Information System"URL":
KEGG Pathways"URL":
Human Metabolome Database"URL":
  • Cell signaling and Ligand transport
  • Structural proteins

REGULATION

DIAGNOSTIC USE

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