Author: Gianpiero Pescarmona
Date: 02/10/2007


Human Protein Atlas

The "Human Proteome" chapters provide a knowledge-based analysis and entry into the Human Protein Atlas from different defined transections of the human tissue proteome. Various human proteomes can be explored such as the housekeeping proteome including proteins expressed in all tissue types, the tissue specific proteome including all proteins that show enriched expression in only one or few tissue types, or as proteomes related to certain features, such as the druggable proteome including all proteins that are targeted by drugs, the cancer proteome including proteins implicated in cancer, and the secretome including all proteins that are secreted. The human proteome can further be explored based on the expression pattern in different organ systems and tissue types, to define the "Organ Proteomes" that describe proteins expressed in diverse cell types that signify different organ structures and functions. Each separate chapter includes a basic description of a defined proteome and includes analyses of expression patterns, gene lists, and examples of protein expression on a cellular level.

Protein Template

ADAM17, AGXT, Albumin, Alkaline Phosphatase, Alpha-Enolase, Apolipoprotein B100, Asialotransferrin, Aurora Kinases, BRCA2, BST1/CD157, Bcl-2, CARBONIC ANHYDRASE II AND ITS DEFICIENCY SYNDROME, COMP, CRP (C-reactive protein), CSPG4, Caspase 3, Caveolin, Cdc42, Chromogranin A, Claudin 1, Collagen, Connexin 43, Cryoglobulins, DNA Cytidine Deaminase (APOBEC-3G), DRP1 And Mitochondrial Fission-Fusion Related Diseases, Defensin, Dystrophin, EMAP and EMAP-like, Ectonucleoside triphosphatase diphosphohydrolase 1 (ENTPD1 or CD39), Elastin, Elongation Factors, Endothelins, Fractalkine (humans) Neurotactin (mice), Frataxin, GTP-ases, Grb-10: the "Hulk-Protein", HMGB1, Haptoglobin, Heat-Shock Proteins, Heparin-binding EGF-like growth factor (HB-EGF) da spostare, Hexosaminidase, Immunoglobulins , Immunophilins, Integrins, JUNO Protein: a Peculiar Folate Receptor Involved in Fertilization, Kallikreins, LACTOFERRIN AND ITS ANTIVIRAL ACTIVITY, LEMD3 , Lactoferrin da cancellare, Lectins, MUC1, Melusin, Merlin (NF2), Metallothioneins, Mitofusin 2 and Charcot Marie Tooth Disease subtype 2A 2, Molecular chaperones, Morgana Protein, Nephrin, Neuroglobin: an endogenous neuroprotectant, Osteopontin, P140Cap, Perforin:pore forming protein, Pikachurin, Polycystin-1 and -2, Protein C da cancellare, Protein-lysine 6-oxidase, Proteina prova, Renalase (MAO-C), SOD, SUPEROXIDE DISMUTASES, Sequestosome 1 (p62), Serine Protease Inhibitors (Serpins), Serine Proteases, Stem cell factor (SCF) and its receptor c-Kit, Sterolins-ABCG5 and ABCG8, Synapsin, Synaptopodin, Syndecan-1 (CD138) , TMEM16A, Tau protein and its role in neurodegenerative diseases., Tesi Campia su MDR, Thrombospondin-1, a key mediator of diabetic complications, Transferrin bk, p130Cas
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