Protein Phosphorylation
Signaling Pathways

Author: Gianpiero Pescarmona
Date: 23/03/2009



Proteins can undergo phosphorylation/dephosphorylation cycles able to modulate their activity in the minutes time range.

Protein kinases are enzymes that transfer a phosphate group from ATP to the hydroxyl group of serine/threonine or tyrosine.
Phosphorylation usually results in a functional change of the target protein by changing enzyme activity, cellular location, or association with other proteins.

The Protein Kinase Resource UCSD


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