STKs - Serine/Threonine Kinases
Protein Phosphorylation

Author: Gianpiero Pescarmona
Date: 03/05/2009


STKs - Serine/Threonine Kinases phosphorylate the OH group of protein serine or threonine.
At least 20% of the human protein kinases are serine/threonine kinases (STK) ???

Activity of these protein kinases can be regulated by specific events

  • DNA damage
  • numerous chemical signals
    • cAMP/cGMP
    • Diacylglycerol
    • Ca2+/calmodulin
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