TFEB
Transcription Factors

DEFINITION

A short protein description with the molecular wheight, isoforms, etc...
Use, when available, the link to Wikipedia (Es Albumin)

External links not available on Wikipedia have to be added here

Database	"URL":
Wikigenes	URL
GeneCards	"URL":
iHOP	URL
OMIM	"URL":

CHEMICAL STRUCTURE AND IMAGES

When relevant for the function

• Primary structure
• Secondary structure
• Tertiary structure
• Quaternary structure

Protein Aminoacids Percentage
The Protein Aminoacids Percentage gives useful information on the local environment and the metabolic status of the cell (starvation, lack of essential AA, hypoxia)

SYNTHESIS AND TURNOVER

mRNA synthesis
protein synthesis
post-translational modifications
degradation

CELLULAR FUNCTIONS

cellular localization,
biological function

• Enzymes
• Cell signaling and Ligand transport
• Structural proteins

REGULATION

TFEB induces PAI-1 expression

Both Max and TFE3 cooperate with Smad proteins to bind the plasminogen activator inhibitor-1 promoter, but they have opposite effects on transcriptional activity. 2003

DIAGNOSTIC USE

file	user	date
TFEB-PAI1-497.gif	gp	28/06/2009