SLC11A1 (NRAMP1)
Iron input

Author: Gianpiero Pescarmona
Date: 02/12/2009

Description

DEFINITION

SLC11A1 (NRAMP1) is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and encodes a multi-pass membrane protein. The protein functions as a divalent transition metal ( iron and manganese ) transporter involved in iron metabolism and host resistance to certain pathogens.

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DatabaseLink
WikigenesHomo Sapiens
WikigenesBos Taurus
WikigenesOvis Aries
GeneCardsURL
iHOPURL
OMIMURL

CHEMICAL STRUCTURE AND IMAGES

When relevant for the function

  • Primary structure
  • Secondary structure
  • Tertiary structure
  • Quaternary structure

SYNTHESIS AND TURNOVER

mRNA synthesis
protein synthesis
post-translational modifications
degradation

CELLULAR FUNCTIONS

cellular localization,
biological function

  • Enzymes
  • Cell signaling and Ligand transport
  • Structural proteins

REGULATION

DIAGNOSTIC USE

Items
Attachments
fileuserdate
NRAMP-DMT1-FP-600.gifgp04/12/2009
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