SLC11A3 (MTP1), Ferroportin
Iron output

Author: Gianpiero Pescarmona
Date: 02/12/2009

Description

DEFINITION

Ferroportin is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters)

External links not available on Wikipedia have to be added here

DatabaseLink
WikigenesHomo Sapiens
GeneCardsURL
iHOPURL
OMIMURL
Entrez GeneURL

CHEMICAL STRUCTURE AND IMAGES

When relevant for the function

  • Primary structure
  • Secondary structure
  • Tertiary structure
  • Quaternary structure


Protein Aminoacids Percentage
The Protein Aminoacids Percentage gives useful information on the local environment and the metabolic status of the cell (starvation, lack of essential AA, hypoxia)

SYNTHESIS AND TURNOVER

mRNA synthesis
protein synthesis
post-translational modifications
degradation

CELLULAR FUNCTIONS

cellular localization,
biological function

  • Enzymes
  • Cell signaling and Ligand transport
  • Structural proteins

REGULATION

MTP1 expression in RES cells of the spleen, liver, and bone marrow is down-regulated by inflammation.

Regulation of Reticuloendothelial Iron Transporter MTP1 (Slc11a3) by Inflammation 2002

DIAGNOSTIC USE

AddThis Social Bookmark Button