Interferon gamma (IFN-gamma)
Interferons (IFNs)

Author: Gianpiero Pescarmona
Date: 08/03/2011

Description

DEFINITION

A short protein description with the molecular wheight, isoforms, etc...
Use, when available, the link to Wikipedia (Es Trypsin)

External links not available on Wikipedia have to be added here

THE GENE

DatabaseLink
WikigenesIFNG
GeneCards"URL":
Your Favorite Gene Sigma"URL":

CHEMICAL STRUCTURE AND IMAGES

When relevant for the function

  • Primary structure
  • Secondary structure
  • Tertiary structure
  • Quaternary structure

Protein Aminoacids Percentage

SYNTHESIS AND TURNOVER

mRNA synthesis
protein synthesis

post-translational modifications
degradation

CELLULAR FUNCTIONS

cellular localization,
biological function

IFNG and MHC-1

  • Enzymes
DatabaseLink
BRENDA - The Comprehensive Enzyme Information System"URL":
KEGG PathwaysIFNG
Human Metabolome Database"URL":
  • Cell signaling and Ligand transport

IFNG is a strong inducer of the following proteins

REGULATION

DIAGNOSTIC USE

Tryptophan forms the substrate for serotonin biosynthesis, but it can alternatively be catabolized to kynurenine (Kyn) by the enzyme indoleamine 2,3-dioxygenase (IDO), the main inducer of which is interferon-gamma

Tryptophan catabolism in females with irritable bowel syndrome: relationship to interferon-gamma, severity of symptoms and psychiatric co-morbidity.2008

Attachments
fileuserdate
IFNG_CHART1.gifgp08/03/2011
IFNG_CHART2.gifgp08/03/2011
IFNG_ch1.pnggp10/07/2016
IFNG_ch2.pnggp10/07/2016
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