Cell Cycle
Cell Proliferation

Author: Gianpiero Pescarmona
Date: 2007-03-18

Description

The cell cycle is the series of events that take place in a eukaryotic cell leading to its replication.
These events can be divided in two brief periods: interphase —during which the cell grows, accumulating nutrients needed for mitosis and duplicating its DNA—and the mitotic (M) phase, during which the cell splits itself into two distinct cells, often called "daughter cells". W

The cell cycle consists of four distinct phases:

  • G1 phase
  • S phase
  • G2 phase (collectively known as interphase)
  • M phase. M phase is itself composed of two tightly coupled processes: mitosis, in which the cell's chromosomes are divided between the two daughter cells, and cytokinesis, in which the cell's cytoplasm divides forming distinct cells.

Activation of each phase is dependent on the proper progression and completion of the previous one. Cells that have temporarily or reversibly stopped dividing are said to have entered a state of quiescence called G0 phase.

Cell cycle checkpoints

G1-> S Enlargement

p53 role

G2 -> M Enlargement

Cell cycle animation
Some connections to textbooks.....

The nucleus structure

Comments
2007-06-26 17:24:03.151408 - costanza cossu

la figura sul ciclo cellulare è sfuocata.
possiamo aggiungerne un'altra? oppure c'è qualche collega che sta lgià avorando su questo?
Costanza Cossu Silvia Bertin

aggiunga all'interno di questo commento. Questa parte è ancora tutta da fare, sviluppi la parte che preferisce.
gpp