Vitamin D Binding Protein (VDBP)
Vitamin D

DEFINITION

A short protein description with the molecular wheight, isoforms, etc...
Use, when available, the link to Wikipedia (Es Trypsin)

External links not available on Wikipedia have to be added here

THE GENE

Database	Link
HGNC	ACADM
Uniprot	"URL":

HGNC includes links to

• BioGPS
• GENATLAS
• GeneCards
• GOPubmed
• H-InvDB
• QuickGO
• Reactome
• Wikigenes includes links to
  • NCBI
  • NCBI SNP
  • iHOP resource
  • OMIM
  • UniProt
  • Ensembl
  • HGNC

CHEMICAL STRUCTURE AND IMAGES

When relevant for the function

• Primary structure
• Secondary structure
• Tertiary structure
  • PDB
• Quaternary structure

Protein Aminoacids Percentage
The Protein Aminoacids Percentage gives useful information on the local environment and the metabolic status of the cell (starvation, lack of essential AA, hypoxia)

Protein Aminoacids Percentage (Width 700 px)

SYNTHESIS AND TURNOVER

mRNA synthesis
protein synthesis

post-translational modifications
degradation

CELLULAR FUNCTIONS

Vitamin D: Metabolism, Molecular Mechanism of Action, and Pleiotropic Effects, 2016

Quantification of Total Vitamin-D-Binding Protein and the Glycosylated Isoforms by Liquid Chromatography–Isotope Dilution Mass Spectrometry, 2017

The role of Gc protein oligosaccharide structure as a risk factor for COPD, 2006

Chapter Two - Desialylation in physiological and pathological processes: New target for diagnostic and therapeutic development, 2019

biological function

• Enzymes

Database	Link
BRENDA - The Comprehensive Enzyme Information System	"URL":
KEGG Pathways	"URL":
Human Metabolome Database	"URL":

• Cell signaling and Ligand transport
• Structural proteins

REGULATION

DIAGNOSTIC USE

Bipolar disorder in youth is associated with increased levels of Vitamin D-binding protein, 2018

Vitamin D Binding Protein (VDBP) and Its Gene Polymorphisms—The Risk of Malignant Tumors and Other Diseases, 2020