DEFINITION
A short protein description with the molecular wheight, isoforms, etc...
Use, when available, the link to Wikipedia (Es Trypsin)
Trace elements in human physiology and pathology: zinc and metallothioneins, 2003
THE GENE
Wikigenes includes links to
- NCBI Gene
- NCBI SNP
- iHOP resource
- OMIM
- SNPedia
- UniProt
- Ensembl
- HGNC
CHEMICAL STRUCTURE AND IMAGES
When relevant for the function
- Primary structure
- Secondary structure
- Tertiary structure
- Quaternary structure
Protein Aminoacids Percentage
The Protein Aminoacids Percentage gives useful information on the local environment and the metabolic status of the cell (starvation, lack of essential AA, hypoxia)
Protein Aminoacids Percentage (Width 700 px)
33% cysteine is the same percentage found in GSH
Which relationship between cell GSH concentration and metallothioneins?
Low Leucine and Met
low mTOR and protein synthesis?
SYNTHESIS AND TURNOVER
mRNA synthesis
protein synthesis
post-translational modifications
degradation
CELLULAR FUNCTIONS
cellular localization,
biological function
Human metallothionein metallomics, 2008
- Cell signaling and Ligand transport
- Structural proteins
REGULATION
DIAGNOSTIC USE
