The chemical reaction
L-tryptophan + O2 --> N-formyl-L-kynurenine
is catalyzed by two different enzymes:
- Indoleamine-pyrrole 2,3-dioxygenase (IDO or INDO EC 1.13.11.52)
- Tryptophan 2,3-dioxygenase (TDO or TDO2 EC 1.13.11.11)
Kynurenine Pathway induction
Multiple Sclerosis Kynurenine
