NADH/NAD
NAD and NADP

Author: Gianpiero Pescarmona
Date: 13/03/2007

Description

NAD description and metabolism

Energy and signal transduction by NAD:Signalling pathways and subcellular compartmentation of NAD biosynthesis

The local NADH/NAD ratio can drive metabolic pathways

  • inositol synthesis is inhibited by NADH and affects
    • IP3 related pathways
    • membrane bound Proteins (with GPI anchor)
  • regulate proteins acetylation and deacetylation (Sirtuins).
  • regulate triglyceride synthesis

  • regulate T4 deiodination to T3

Glucose restriction blocks skeletal muscle cell differentiation 2008

Attachments
fileuserdate
NAD-NADH.gifgp10/10/2007
NADH_NAD_700.gifgp10/10/2007
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