The "Human Proteome" chapters provide a knowledge-based analysis and entry into the Human Protein Atlas from different defined transections of the human tissue proteome. Various human proteomes can be explored such as the housekeeping proteome including proteins expressed in all tissue types, the tissue specific proteome including all proteins that show enriched expression in only one or few tissue types, or as proteomes related to certain features, such as the druggable proteome including all proteins that are targeted by drugs, the cancer proteome including proteins implicated in cancer, and the secretome including all proteins that are secreted. The human proteome can further be explored based on the expression pattern in different organ systems and tissue types, to define the "Organ Proteomes" that describe proteins expressed in diverse cell types that signify different organ structures and functions. Each separate chapter includes a basic description of a defined proteome and includes analyses of expression patterns, gene lists, and examples of protein expression on a cellular level.
